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Sunday, May 10, 2020

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A New Cancer Treatment That Is Faster, More Efficient and Less Risky Is Coming: Bacteria Bombs

A scanning electron micrograph of immune cells, blue, attacking cancer cells. Tumors may elude the immune system, but researchers are harnessing reprogrammed bacteria to destroy cancer cells in mice. <a href="https://www.nytimes.com/2019/07/03/science/cancer-bacteria-immune-system.html">Related Article</a>
A New Cancer Treatment That Is Faster, More Efficient and Less Risky Is Coming: Bacteria Bombs

Bacteria are usually thought of as microscopic, disease-causing nuisances. They have long been seen as something that needs to be washed away with soap and warm water, or killed en masse with hand sanitizer. But what if these stigmatized organisms could be used to fight cancer, the stubborn killer devastating millions of people? Scientists at the University of California, led by Jeff Hasty, are working to genetically engineer bacteria that will infiltrate tumors and kill them. Combined with conventional treatment such as chemotherapy, researchers are hoping bacteria will be very effective at killing tumors and, further, stopping them from spreading. If proven safe and effective, this bacterial treatment could provide a vital victory in the war against cancer.

The immune system regularly patrols the body to find and destroy cancerous cells, but tumors can disguise themselves as normal cells by releasing a protein that tells the body to leave the tumor alone. And so, the tumor hides in plain sight, invading the healthy tissue around it. Tumors use blood vessels that branch all over the surface of the tumor to steal resources...

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