Study of climate change could lead to understanding future of infectious disease
Over the past 34 years, rainfall in Uganda has decreased by about 12 percent even though many of the global climate models predict an increase in rainfall for the area, according to an international team of researchers. Rainfall levels in Uganda impact agriculture, food security, wildlife habitats and regional economics as well as the prevalence of certain diseases.
"We didn't plan to study the climate," said Steven J. Schiff, Brush Chair Professor of Engineering in the Departments of Neurosurgery, Engineering Science and Mechanics and Physics, Penn State. "But we realized we needed the information to study infections. The biggest need for infant brain surgery in the developing world is infection-caused hydrocephalus."
While there are congenital cases of hydrocephalus, infectious disease causes the majority of cases in Uganda. Infections are the cause of large numbers of infant deaths during the first four weeks of life and half those deaths take place in sub-Saharan Africa. Those who do not die, often develop hydrocephalus, a buildup of fluids in the brain cavities that can cause head deformation and cognitive deficits. It is estimated that there are 100,000 to 200,000 such cases each year in sub-Saharan Africa.
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